Synucleins Peptides Blog~ Synucleins Research Papers

Synucleins Peptides Blog~ Synucleins Research Papers

1.

Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation

Bobby Thomas, Allen S. Mandir, Neva West, Ying Liu, Shaida A. Andrabi, Wanda Stirling, Valina L. Dawson, Ted M. Dawson, and Michael K. Lee

PLoS One. 2011; 6(1): e16706. Published online 2011 January 31. doi: 10.1371/journal.pone.0016706

PMCID: 

PMC3031616

AbstractFull TextPDF–1.4M

2.

α-Synuclein and Its A30P Mutant Affect Actin Cytoskeletal Structure and Dynamics

Vítor L. Sousa, Serena Bellani, Maila Giannandrea, Malikmohamed Yousuf, Flavia Valtorta, Jacopo Meldolesi, and Evelina Chieregatti

Mol Biol Cell. 2009 August 15; 20(16): 3725–3739. doi: 10.1091/mbc.E08-03-0302

PMCID: 

PMC2777932

AbstractFull TextPDF–4.1MSupplementary Material

3.

Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain

Latha Devi, Vijayendran Raghavendran, Badanavalu M. Prabhu, Narayan G. Avadhani, and Hindupur K. Anandatheerthavarada

J Biol Chem. 2008 April 4; 283(14): 9089–9100. doi: 10.1074/jbc.M710012200

PMCID: 

PMC2431021

AbstractFull Text

4.

αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

Becket Greten-Harrison, Manuela Polydoro, Megumi Morimoto-Tomita, Ling Diao, Andrew M. Williams, Esther H. Nie, Sachin Makani, Ning Tian, Pablo E. Castillo, Vladimir L. Buchman, and Sreeganga S. Chandra

Proc Natl Acad Sci U S A. 2010 November 9; 107(45): 19573–19578. Published online 2010 October 25.doi: 10.1073/pnas.1005005107

PMCID: 

PMC2984188

AbstractFull TextPDF–1.1MSupplementary Material

5.

Direct Transfer of α-Synuclein from Neuron to Astroglia Causes Inflammatory Responses in Synucleinopathies

He-Jin Lee, Ji-Eun Suk, Christina Patrick, Eun-Jin Bae, Ji-Hoon Cho, Sangchul Rho, Daehee Hwang, Eliezer Masliah, and Seung-Jae Lee

J Biol Chem. 2010 March 19; 285(12): 9262–9272. Published online 2010 January 13. doi: 10.1074/jbc.M109.081125

PMCID: 

PMC2838344

AbstractFull TextSupplementary Material

6.

Localization of Synucleins in the Mammalian Cochlea

O. Akil, C. M. Weber, S. N. Park, N. Ninkina, V. Buchman, and L. R. Lustig

J Assoc Res Otolaryngol. 2008 December; 9(4): 452–463. Published online 2008 July 30. doi: 10.1007/s10162-008-0134-y

PMCID: 

PMC2580813

AbstractFull TextPDF–596K

7.

α-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREs

Nandhakumar Thayanidhi, Jared R. Helm, Deborah C. Nycz, Marvin Bentley, Yingjian Liang, and Jesse C. Hay

Mol Biol Cell. 2010 June 1; 21(11): 1850–1863. doi: 10.1091/mbc.E09-09-0801

PMCID: 

PMC2877643

AbstractFull TextPDF–2.8MSupplementary Material

8.

ALPHA-SYNUCLEIN-IMMUNOPOSITIVE MYENTERIC NEURONS AND VAGAL PREGANGLIONIC TERMINALS: AUTONOMIC PATHWAY IMPLICATED IN PARKINSON’S DISEASE?

Robert J. Phillips, Gary C. Walter, Sarah L. Wilder, Elizabeth A. Baronowsky, and Terry L. Powley

Neuroscience. Author manuscript; available in PMC 2009 May 15.

Published in final edited form as: Neuroscience. 2008 May 15; 153(3): 733–750. Published online 2008 March 18.doi: 10.1016/j.neuroscience.2008.02.074

PMCID: 

PMC2605676

AbstractFull TextPDF–3.3M

9.

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

Preeti J Khandelwal, Sonya B Dumanis, Li Rebekah Feng, Kathleen Maguire-Zeiss, GW Rebeck, Hilal A Lashuel, and Charbel EH Moussa

Mol Neurodegener. 2010; 5: 47. Published online 2010 November 4. doi: 10.1186/1750-1326-5-47

PMCID: 

PMC2987994

AbstractFull TextPDF–2.5M

10.

Parkin Deficiency Delays Motor Decline and Disease Manifestation in a Mouse Model of Synucleinopathy

Margot Fournier, Jérémie Vitte, Jérôme Garrigue, Dominique Langui, Jean-Philippe Dullin, Françoise Saurini, Naïma Hanoun, Fernando Perez-Diaz, Fabien Cornilleau, Chantal Joubert, Héctor Ardila-Osorio, Sabine Traver, René Duchateau, Cécile Goujet-Zalc, Katerina Paleologou, Hilal A. Lashuel, Christian Haass, Charles Duyckaerts, Charles Cohen-Salmon, Philipp J. Kahle, Michel Hamon, Alexis Brice, and Olga Corti

PLoS One. 2009; 4(8): e6629. Published online 2009 August 14. doi: 10.1371/journal.pone.0006629

PMCID: 

PMC2722082

AbstractFull TextPDF–2.0MSupplementary Material

11.

Pathological Modifications of α-Synuclein in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Treated Squirrel Monkeys

Alison L. McCormack, Sally K. Mak, Maryam Shenasa, William J. Langston, Lysia S. Forno, and Donato A. Di Monte

J Neuropathol Exp Neurol. Author manuscript; available in PMC 2009 September 16.

Published in final edited form as: J Neuropathol Exp Neurol. 2008 August; 67(8): 793–802.doi: 10.1097/NEN.0b013e318180f0bd

PMCID: 

PMC2745435

AbstractFull TextPDF–2.5M

12.

Parkinson's Disease-Related Protein, α-Synuclein, in Malignant Melanoma

Yasuhiro Matsuo and Tetsu Kamitani

PLoS One. 2010; 5(5): e10481. Published online 2010 May 5. doi: 10.1371/journal.pone.0010481

PMCID: 

PMC2864738

AbstractFull TextPDF–1.6M

13.

Detecting Morphologically Distinct Oligomeric Forms of α-Synuclein

Sharareh Emadi, Srinath Kasturirangan, Min S. Wang, Philip Schulz, and Michael R. Sierks

J Biol Chem. 2009 April 24; 284(17): 11048–11058. doi: 10.1074/jbc.M806559200

PMCID: 

PMC2670110

AbstractFull Text

14.

Transglutaminase-mediated Intramolecular Cross-linking of Membrane-bound α-Synuclein Promotes Amyloid Formation in Lewy Bodies

Zoltán Nemes, Goran Petrovski, Maarten Aerts, Kjell Sergeant, Bart Devreese, and László Fésüs

J Biol Chem. 2009 October 2; 284(40): 27252–27264. Published online 2009 August 3. doi: 10.1074/jbc.M109.033969

PMCID: 

PMC2785653

AbstractFull Text

15.

Lysosomal Degradation of α-Synuclein in Vivo

Sally K. Mak, Alison L. McCormack, Amy B. Manning-Boğ, Ana Maria Cuervo, and Donato A. Di Monte

J Biol Chem. 2010 April 30; 285(18): 13621–13629. Published online 2010 March 3. doi: 10.1074/jbc.M109.074617

PMCID: 

PMC2859524

AbstractFull TextSupplementary Material

16.

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

Zhen Hong, Min Shi, Kathryn A. Chung, Joseph F. Quinn, Elaine R. Peskind, Douglas Galasko, Joseph Jankovic, Cyrus P. Zabetian, James B. Leverenz, Geoffrey Baird, Thomas J. Montine, Aneeka M. Hancock, Hyejin Hwang, Catherine Pan, Joshua Bradner, Un J. Kang, Poul H. Jensen, and Jing Zhang

Brain. 2010 March; 133(3): 713–726. Published online 2010 February 15. doi: 10.1093/brain/awq008

PMCID: 

PMC2842513

AbstractFull TextPDF–1.0MSupplementary Material

17.

γ-Synucleinopathy: neurodegeneration associated with overexpression of the mouse protein

Natalia Ninkina, Owen Peters, Steven Millership, Hatem Salem, Herman van der Putten, and Vladimir L. Buchman

Hum Mol Genet. 2009 May 15; 18(10): 1779–1794. Published online 2009 February 26. doi: 10.1093/hmg/ddp090

PMCID: 

PMC2671987

AbstractFull TextPDF–727KSupplementary Material

18.

Mitochondrial translocation of α-synuclein is promoted by intracellular acidification

Nelson B. Cole, Diane DiEuliis, Paul Leo, Drake C. Mitchell, and Robert L. Nussbaum

Exp Cell Res. Author manuscript; available in PMC 2009 June 10.

Published in final edited form as: Exp Cell Res. 2008 June 10; 314(10): 2076–2089. Published online 2008 March 28.doi: 10.1016/j.yexcr.2008.03.012

PMCID: 

PMC2483835

AbstractFull TextPDF–1.7MSupplementary Material

19.

γ-Synuclein as a marker of retinal ganglion cells

Irina Surgucheva, Alejandra D. Weisman, Jeffrey L. Goldberg, Alexander Shnyra, and Andrei Surguchov

Mol Vis. 2008; 14: 1540–1548. Published online 2008 August 22.

PMCID: 

PMC2518532

AbstractFull TextPDF–2.6M

20.

A Cellular Model To Monitor Proteasome Dysfunction by α-Synuclein

Takashi Nonaka and Masato Hasegawa

Biochemistry. 2009 August 25; 48(33): 8014–8022. Published online 2009 July 24. doi: 10.1021/bi900619j

PMCID: 

PMC2728579

AbstractFull TextPDF–3.4MSupplementary Material